We have had many patients in the past ask whether or not you can mix Botox with Dysport for wrinkle reduction. The answer is – yes! There is no scientific and/or medical evidence that suggests there would be any problem with mixing these two neurotoxins together. Both Botox and Dysport work in a similar manner to modulate the nerve endings so that muscle contraction is reduced in the area of excess wrinkle formation. As long as your cosmetic doctor is careful in terms of dosing the medication, there should be no significant adverse effect. When does this situation arise? If, for example, someone goes to another office to get either Botox or Dysport and is not happy with the cosmetic outcome. They can readily go to a different office and get the neurotoxin they didn’t get injected the first time around.